a,106 participants for nearly four years, with quarterly healthy visits and dense sampling during stress events. b, Summary of visits in each category and categorization of participants as insulinsensitive or insulin-resistant. c, Sample sources, types of multi-omic assay and number for each data type profiled per visit. d, Conceptual illustration of the data structure for downstream analysis. Supplementary Table 3 lists the number of visits and assays profiled for each participant.
3 0 M AY 2 0 1 9 | VO L 5 6 9 | N AT U RE | 6 6 3 2.代谢病—肥胖:肥胖是与肠道微生物关系非常密切的一类疾病。我们可以研究遗传、环境、饮食、运动等因素对肥胖及宿主宏病毒组的影响,也可以通过动物模型研究病毒组与肥胖的关系。在粪便病毒组移植方面也有研究报道。另外,研究病毒组与细菌相互作用、病毒组与宿主相互作用等也可以进一步了解病毒对肥胖或相关疾病的影响机制。